SCIENCE INNOVATION TO MARKET INNOVATION: LIPINUTRAGEN
The multidisciplinary approach taken by our group has proven effective for industrial and commercial application, producing results that are applicable to society’s needs. This approach is perfectly aligned with Horizon2020’s goals for innovation, and turning research output into economic growth within the EU. The main strategic knowledge and technology transferred to market are represented with the company LIPINUTRAGEN located in Bologna and born as a spin-off of Chatgilialoglu & Ferreri’s research in lipidomics, officially recognized by the CNR (approval #101 July 13, 2005 from the CNR Board of Directors).
It is the first company to develop NUTRILIPIDOMICS, an innovative approach linking membrane-based diagnostics to nutraceuticals and nutrition for a personalized strategy in health care.
The logo of the company contains the concept of CELL MEMBRANE BALANCE, a milestone of molecular medicine, which stated that: “HEALTH BEGINS FROM THE CELL HEALTH”.
From CNR research into membrane stress, signaling and remodeling processes connected with metabolic and environmental conditions (see MEMBRANE LIPIDOMICS), it was envisaged that the membrane of the mature red blood cells (RBC) can be used as reporter of the metabolic and nutritional status of individuals. The CNR research developed the knowledge in lipidomics and Lipinutragen R&D developed the robotics (TECAN) for the cell selection and work-up of RBC membranes, which is an exclusivity of the company.
The Company has two types of lipidomic analysis on the market (Fat Profile and fatpharmacy) and has a section dedicated to innovative nutraceuticals and nutrition targeted to cell membrane. It has an R&D&I section, a Lipidomic Laboratory authorized by the Health Ministry and offices for a total of 12 employees.
For a full description see the website: www.lipinutragen.it
Review:
Role of fatty acid-based functional lipidomics in the development of molecular diagnostic tools
Ferreri, C.; Chatgilialoglu, C. Expert Rev. Mol. Diagn. 2012, 12, 767–780.
Book:
Membrane Lipidomics for Personalized Health
Authors: Carla Ferreri and Chryssostomos Chatgilialoglu
John Wiley & Sons Ltd, Chichester (UK), 2015.
Interviews:
Lipidomics- the future of personalized medicine?
Ferreri, C.; Chatgilialoglu, C. Tecan Journal 2018, 2, 20-21.
Profiling cell membranes
Chatgilialoglu, C.; Ferreri, C. Impact 2017, 90-92.
Recent Publications:
High predictive values of RBC membrane-based diagnostics by biophotonics in an integrated approach for Autism Spectrum Disorders
Giacometti, G.; Ferreri, C.; Sansone, A.; Chatgilialoglu, C.; Marzetti, C.; Spyratou, E.; Georgakilas, A.G.; Marini, M.; Abruzzo, P.M.; Bolotta, A.; Ghezzo, A.; Minguzzi, R.; Posar, A.; Visconti, P. Sci. Rep. 2017, 7, article 9854.
Fatty acids in membranes as homeostatic, metabolic and nutritional biomarkers: recent advancements in analytics and diagnostics
Ferreri, C.; Masi, A.; Sansone, A.; Giacometti, G.; Larocca, A.V.; Menounou, G.; Scanferlato, R.; Tortorella, S.; Rota, D.; Conti, M.; Deplano, S.; Louka, M.; Maranini, A.R.; Salati, A.; Sunda, V.; Chatgilialoglu, C. Diagnostics 2017, 7, 1-14.
Hexadecenoic fatty acid isomers in human blood lipids and their relevance for interpretation of lipidomic profiles
Sansone, A.; Tolika, E.; Louka, M.; Sunda, V.; Deplano, S.; Melchiorre, M.; Anagnostopoulos, D.; Chatgilialoglu, C.; Formisano, C.; Di Micco, R.; Faraone Mennella, R.; Ferreri, C. PLoS One 2016, 11, article e0152378.
Nutrition and reproductive health: sperm vesrus erythrocyte lipidomic profile and ω-3 intake
Mendeluk G. R.; Cohen, M. I.; Ferreri, C.; Chatgilialoglu, C. J. Nutr. Metabol. 2015, article 670526.